Grace imaging



Exploring new frontiers
within human bodies
with new vital signs

Data is just data without interpretation
We use our medical expertise and technology,
and transform data into insight
that adds value to our healthcare and daily life.


Sweat inside every one of us
It is now attracting more attention than ever as a new form of vital sign.

We are commercializing the world’s first wearable device that
monitors change in amount fo lactic acid within our sweat.
With this device, we aim to medically assess and quantify every physical activity.
We believe there still exsits unknowns within our body.
We use our medical expertise and technology,
and transform data into insight
that adds value to our healthcare and daily life.


We visualize “fatigue” from the change in lactic acid content in sweat.
Our unprecedented technology, powered by chemistry and electronics.

Ever increasing number of heart failure patients on cardiac rehabilitation program.
Professional athletes going through vigorous training everyday.
Workers exposed to high-risk, high-physically demanding environment.
We all require better understanding of “fatigue” one way or another.
Our device will let us simultaneously monitor the lactic acid content in sweat,
which changes depending on the degree of physical activity.
By delivering our technology, we will present new understanding of body functions,
and bring new lifestyle, new form of healthcare, and new ways of enjoying sports.

Sweat Lactate Sensor system (device, electrode, application)



Anaerobic threshold using sweat lactate sensor under hypoxia
H.Okawara, Y.Iwasawa, T.Sawada, K.Sugai, K.Daigo, Y.Seki, G.Ichihara, D.Nakashima, M.Sano, M.Nakamura, K.Sato, K.Fukuda, Y.Katsumata
Sci Rep. 2023 Dec 21;13(1):22865 | doi: 10.1038/s41598-023-49369-7. PMID: 38129473; PMCID: PMC10739691
Estimation of maximal lactate steady state using the sweat lactate sensor
Y.Muramoto, D.Nakashima, T.Amano, T.Harita, K.Sugai, K.Daigo, Y.Iwasawa, G.Ichihara, H.Okawara, T.Sawada, A.Kinoda, Y.Yamada, T.Kimura, K.Sato, Y.Katsumata
Sci Rep. 2023 Jun 26;13(1):10366 | doi: 10.1038/s41598-023-36983-8. PMID: 37365235; PMCID: PMC10293173
Implications of the Onset of Sweating on the Sweat Lactate Threshold
Y.Maeda, H.Okawara, T.Sawada, D.Nakashima, J.Nagahara, H.Fujitsuka, K.Ikeda, S.Hoshino, Y.Kobari, Y.Katsumata, M.Nakamura, T.Nagura
Sensors. 2023 Mar 23;23(7):3378 | doi: 10.3390/s23073378. PMID: 37050438; PMCID: PMC10098635


Constant Load Pedaling Exercise Combined with Electrical Muscle Stimulation Leads to an Early Increase in Sweat Lactate Levels
T.Sawada, H.Okawara, D.Nakashima, K.Ikeda, J.Nagahara, H.Fujitsuka, S.Hoshino, Y.Maeda, Y.Katsumata, M.Nakamura, T.Nagura
Sensors. 2022 Dec 7;22(24):9585 | doi: 10.3390/s22249585. PMID: 36559954; PMCID: PMC9784187
Kinetic changes in sweat lactate following fatigue during constant workload exercise
H.Okawara, T.Sawada, D.Nakashima, Y.Maeda, S.Minoji, T.Morisue, Y.Katsumata, M.Matsumoto, M.Nakamura, T.Nagura
Physiol Rep. 2022 Jan;10(2):e15169 | doi: 10.14814/phy2.15169. PMID: 35043587; PMCID: PMC8767313


Laminar flow ventilation system to prevent airborne infection during exercise in the COVID-19 crisis: A single-center observational study
Y.Katsumata, M.Sano, H.Okawara, T.Sawada, D.Nakashima, G.Ichihara, K.Fukuda, K.Sato, E.Kobayashi
PLoS One. 2021 Nov 10;16(11):e0257549 | doi: 10.1371/journal.pone.0257549. PMID: 34758032; PMCID: PMC8580245
A novel device for detecting anaerobic threshold using sweat lactate during exercise
Y.Seki, D.Nakashima, Y.Shiraishi, T.Ryuzaki, H.Ikura, K.Miura, M.Suzuki, T.Watanabe, T.Nagura, M.Matsumato, M.Nakamura, K.Sato, K.Fukuda, Y.Katsumata
Sci Rep. 2021 Mar 2;11(1):4929 | doi: 10.1038/s41598-021-84381-9. PMID: 33654133; PMCID: PMC7925537


We aim to expand the possibilities of human body with sweat.
And our lab is working on various projects.


Medical understanding and social development.
We don’t just collect data, but use the data.

There exists technologies to acquire data, and are lot of research projects on vital signs.
But they are never used in our real life.
We don’t let data sit as data.
Everyday, we bring sit together with medical experts,
continuously assessing data on hand
to bring meaningful changes in our life.

Name of company
Grace imaging, Inc.
Representative Director
Daisuke Nakashima
2F Clinical Research Bldg.
Dept. of Orthopaedic Surgery, Keio Univ. School of Medicine,
35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582 JAPAN
Traffic Access
7 minutes from Shinanomachi-Station of JR Sobu-Line
6 minutes from Kokuritsukyogijou-Station of Oedo-Line
10 minutes form Yotsuya-Sanchome-Station of Marunouchi-Line
Date of foundation
July 2nd 2018
Number of employee
13 employees
Capital stock
100,000,000 JPY(Excluding capital reserve)
Our Business
Development and Provision of analysis and evaluation services for fatigue using the device that measures lacate acid content in sweat.



We are always looking for talents to join our team, as we work on new product development.
Interested? Please click the link below for details.


Want to talk to us?
Please fill in the form below to contact us.